Preventing Infection After Transmetatarsal Amputation (TMA): What We Know
- 5 days ago
- 1 min read
Since infection is a common indication for TMA, patients undergoing this procedure face a high risk of developing surgical site infections.
Study design and scope
A systematic review of global databases identified five studies (two clinical trials, three observational) covering 378 procedures and four interventions to reduce surgical site infections following TMA.
Key outcomes
Antibiotic beads embedded in tissue before closure reduced infection rates.
Negative Pressure Wound Therapy (NPWT) reduced infections and sped healing.
Post-op antibiotics showed mixed results across studies.
Skin preparation methods showed no significant difference.
In practice
A deliberate infection-prevention strategy is superior to closure and hope. The strongest evidence supports antibiotic beads and negative pressure wound dressings.
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