top of page

How Reliable Is the Data?

Concern has been raised regarding the quality of foot and ankle research. Authors have eloquently highlighted inherent biases in study design, effects on data presentation, as well as statistical manipulation i.e. “P-hacking.” Some have even called for statistical significance to be moved from P <0.05 to P <0.005.


Catch the biases if you can


Continuing the critical appraisal of the data is the recently published “The Statistical Fragility of Operative vs. Nonoperative Management for Achilles Tendon Rupture: A Systematic Review of Comparative Studies,” by Nathan P. Fackler et al.


Using the Fragility Index, the researchers showed that in 17 studies, including 10 randomized level controlled studies and over 40 outcome variables, the efficacy of operative versus nonoperative treatment of Achilles ruptures is not as statistically stable as previously predicted.

In other words, like so many other foot and ankle controversies, the debate continues.

5 views0 comments

Recent Posts

See All

Equity is the Buzzward, Including NIH Funding

Recent data shows: 2% of NIH-supported institutions get about 53% of all research project grant dollars 10 top-funded institutions each get more dollars than do each of 35 to 40 entire states With the

Wound Care Business in Crisis

BioAventis has agreed to sell its wound business to LifeNet Health, which includes skin substitutes TheraSkin and TheraGenesis. The transaction includes a total cash consideration of $85 million. Indu

Foot and Ankle Leadership News

Dr. Ned Amendola MD, FAAOS, FRCS(C) from Duke University was named second vice president of the American Academy of Orthopedic Surgeons (AAOS) and will ascend to president in 2025-2026. Fellowship tra

FIX Masthead 2000x318 v2.jpg
bottom of page