We all want an effective approach to improve outcomes with osteochondral lesions of the talus. CBMA, rich in stem cells and cartilage-promoting factors, has emerged as a potential solution, but clinical evidence remains limited. A systematic review of 15 studies (PubMed, Scopus, Cochrane) examining functional and pain outcomes after CBMA-assisted surgical treatment of osteochondral talus lesions in adults. CBMA improved pain and function across multiple applications – standa